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. 2020 Sep 18;9:e52707. doi: 10.7554/eLife.52707

Figure 6. Synergistic splicing is distinct from differential expression and associated with synergy.

(A) Number of synergistically expressed and synergistically spliced genes in TM in MCF7 cells over time; shaded areas correspond to the Venn diagram for 3 hr. (B) Relationship of Excess Over Bliss score with the number of synergistically spliced genes in MCF7. (See also Supplementary file 9).

Figure 6.

Figure 6—figure supplement 1. Differential and synergistic splicing in MCF7 cells.

Figure 6—figure supplement 1.

(A-C) Number of differentially spliced genes over time with Venn diagrams of differentially spliced genes at 3 hr in (A) T, M, and TM; (B) T, W, and TW; and (C) M, W, and MW. The area represented in each color is in proportion to the number of genes in the corresponding color of the Venn diagram; blue areas represent synergistic genes. (D–F) Number of synergistically expressed and synergistically spliced genes in (D) TM, (E) TW, and (F) MW over time; shaded areas correspond to the Venn diagrams for 3 hr. (See also Source data 8).