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. 2020 Sep 23;11:2108. doi: 10.3389/fimmu.2020.02108

Figure 7.

Figure 7

Reconciliation of our staining plus qRT-PCR data from FACS-sorted CD32-mid and CD32-high Kupffer cells with data from two published scRNAseq studies reveals broad agreement. Genes highlighted in blue seem to be diagnostic of a subset optimized for endocytosis and immune suppression, which genes highlighted in red are diagnostic for a subset optimized for inflammation and anti-microbial activity. Genes that are disparate between the different studies are highlighted in purple. Note in particular that CD163 expression in our study was discordant with the two single cell RNA sequencing studies.