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. 2020 Sep 25;11:532199. doi: 10.3389/fphar.2020.532199

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Copyright © 2020 Safar, El-Hashim, Amoudy and Mustafa

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of Rv3619c/Freund’s Incomplete Adjuvant (IFA) alone and in combination with low dose dexamethasone (DEX) (0.5 mg) treatment on Th2 cytokine (IL-5) secretion from spleen cells of ovalbumin (OVA)-challenged mice. Immunization of mice with Rv3619c/IFA showed a significant inhibition of secretion of Th2 cytokine (IL-5). Immunization with Rv3619c/IFA in combination with dexamethasone (0.5 mg) treatment did have any greater effects on the IL-5 levels. Data are expressed as mean ± SEM (n = 10). ^#P < 0.05 versus time-matched PBS-challenged mice. *P < 0.05 versus time-matched OVA-challenged mice.