Figure 3.

Microglial activation after IC transplantation or IV injection of hUC-MSCs in MCAo rats. (A) Representative confocal images of dual IHC for ED1 (green) and Iba-1 (red). DAPI (blue) counterstain. Scale bar = 50 μm. (B) Schematic images of quantitative analyses for five regions of interest (ROIs) in peri-infarct border zones. (C) Quantitative analyses of ED1⁺ cell proportionalities in four study groups (n = 5 each). (D) Quantitative analyses of Iba-1⁺ cell proportionalities in four study groups (n = 5 each). (E) Quantitative analyses of ED1⁺/Iba-1⁺ cell proportionalities in four study groups (n = 5 each). Data expressed as mean ± SEM values. *p < 0.05.