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. 2020 Sep 25;14:546659. doi: 10.3389/fncel.2020.546659

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Copyright © 2020 Noh, Oh, Park and Song.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Microglial polarization after IC transplantation or IV injection of hUC-MSCs in MCAo rats. (A) Representative confocal images of dual IHC for ED1 (green) and CD206 (red). (B) Schematic images of quantitative analyses for five ROIs in peri-infarct border zones. (C) Quantitative analyses of ED1⁺/CD206⁺ cell proportionalities in four study groups (n = 5 each). (D) Representative confocal images of dual IHC for ED1 (green) and iNOS (red). DAPI (blue) counterstain. Scale bar = 50 μm. (E) Schematic images of quantitative analyses for five ROIs in peri-infarct border zones. (F) Quantitative analyses of ED1⁺/iNOS⁺ cell proportionalities in four study groups (n = 5 each). DAPI (blue) counterstain. Scale bar = 50 μm. Data expressed as mean ± SEM values. *p < 0.05.