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. 2020 Sep 25;14:546659. doi: 10.3389/fncel.2020.546659

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Copyright © 2020 Noh, Oh, Park and Song.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Glial scarring after IC transplantation or IV injection of hUC-MSCs in MCAo rats. (A) Schematic images of quantitative analyses for two ROIs in peri-infarct border zones. White dashed boxes denote ROIs for measuring GFAP⁺ glial scars within the peri-infarct cortex (i) and striatum (ii). Scale bar = 100 μm. (B) Representative confocal images of GFAP⁺ glial scars (green) in peri-infarct border zones of four study groups. (C) Quantitative analyses of GFAP+ glial scars in the peri-infarct cortex (left) and striatum (right) shown by four study groups (n = 5 each). Data expressed as mean ± SEM values. *p < 0.05.