Table 5.
Univariate and multivariate analysis for factors effecting delayed initiation (≥ 8 weeks) of AC
| Variables | Univariate HR p value | Multivariate HR p value |
|---|---|---|
| Age | ||
|
< 75 ≥ 75 |
1 (Ref) 0.932 0.798 |
NS |
| Socioeconomic status | ||
|
High income Low to moderate income |
1 (Ref) 1.979 0.002 |
1 (Ref) 2.159 0.001 |
| Education | ||
|
High school/undergraduate Illiterate/primary school |
1 (Ref) 1.136 0.526 |
NS |
| Cancer type | ||
|
Colon Rectal |
1 (Ref) 1.014 0.944 |
NS |
| Serum CEA | ||
|
Normal Elevated |
1 (Ref) 1.376 0.118 |
NS |
| Serum NLR | ||
|
< 2.4 ≥ 2.4 |
1 (Ref) 1.131 0.527 |
NS |
| Complication | ||
|
No Yes |
1 (Ref) 2.451 0.002 |
1 (Ref) 2.263 0.006 |
| HADS-anxiety | ||
|
No (< 11) Yes (≥ 11) |
1 (Ref) 2.046 0.004 |
NS |
| HADS-depression | ||
|
No (< 11) Yes (≥ 11) |
1 (Ref) 2.984 0.017 |
NS |
| SCNS-SF34 score | ||
|
Low need High need |
1 (Ref) 3.182 < 0.001 |
1 (Ref) 2.905 < 0.001 |
HR, hazard ratio; CEA, carcinoembryonic antigen; AC, adjuvant chemotherapy; NLR, neutrophil to lymphocyte ratio; NS, not significant