Fig. 4. Microstate transition probabilities are non-random and are abnormal in MDD.

a Matrix showing the observed transition probabilities given the known distribution of microstate labels minus the expected transition probabilities. Positive values indicate more transitions than would be expected by chance, negative values indicate fewer transitions. Colored boxes and text indicate statistically significant differences as calculated by Bonferroni-adjusted t-tests. b Comparisons of observed minus expected transitions between HC, MDD, and rMDD groups. Positive values indicate that there are more transitions in the first listed group compared to the second, red values indicate that there are more transitions in the second listed group compared to the first. Colored boxes and text indicate statistically significant differences as calculated by ANOVAs with post-hoc HSD test (p < 0.05).