Table 3.

pH: Comparison of Oxytocin Gel versus Aqueous Hypromellose-Based Vaginal Gel Using the Change from Baseline Within (Wilcoxon Signed Rank Test) and Between (Wilcoxon Rank Sum Test) the Groups

Group	Time	Mean	P-value
Oxytocin gel (n=79)	Baseline	7.01	NA
	Week 4	6.64	NA
	Week 12	6.56	NA
	Week 4 - baseline	−0.38	0.0011
	Week 12 - baseline	−0.46	0.0002
Aqueous Hypromellose-based vaginal gel (n=78)	Baseline	7.00	NA
	Week 4	6.47	NA
	Week 12	6.27	NA
	Week 4 - baseline	−0.53	0.0000
	Week 12 - baseline	−0.73	0.0000
Oxytocin gel compared to Aqueous Hypromellose-based vaginal gel. The mean values are calculated by subtracting the mean values for each treatment group (Oxytocin gel minus Aqueous Hypromellose-based vaginal gel)	Baseline	0.01	0.6965
	Week 4	0.17	0.3293
	Week 12	0.29	0.1524
	Week 4 - baseline	0.16	0.4548
	Week 12 - baseline	0.28	0.1350