Table 1.
Heavy metal levels and label information of local manufactured painkiller drugs in Nigeria.
| S/n | Product Code | Pharmacological Effect | Country of Manufacture | Nafdac. Reg. No | Batch No | Man.Date | Exp. Date | Heavy Metals (Mg/kg) |
|||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| As | Cd | Cr | Hg | Ni | Pb | ||||||||
| 1. | 01 | (I)Analgesic (ii)Antipyretic | NIGERIA | 04-0411 | 55571 | 10/14 | 10/19 | 0.350 | ND | ND | 0.470 | 0.125 | ND |
| 2. | 02 | (i)Analgesic (ii)Ant Ipyretic | NIGERIA | 04-0633 | 0336 | 7/14 | 6/19 | 0.150 | 0.013 | ND | 0.108 | 0.100 | ND |
| 3. | 03 | (i)Analgesic (ii)Antipyretic | NIGERIA | 04-7366 | T621112 | 11/12 | 10/17 | 0.350 | 0.020 | 6.637 | ND | 0.434 | ND |
| 4. | 04 | (i)Analgesic (ii)Antipyretic | NIGERIA | B4-1774 | 493 | 10/14 | 9/18 | 0.250 | ND | 2.318 | 0.100 | 0.200 | ND |
| 5. | 05 | (i)Analgesic (ii)Antipyretic | NIGERIA | B4-1593 | T4048 | 8/14 | 7/17 | 0.050 | ND | ND | 0.151 | 0.173 | 2.47 |
| 6. | 060 | (i)Analgesic (ii) Antipyretic | NIGERIA | A4-5653 | 349 | 8/14 | 7/17 | 0.150 | 0.065 | ND | 0.069 | 0.223 | ND |
| 7. | 070 | (i)Analgesic (ii) Antipyretic | NIGERIA | A4-0579 | 373 | 11/14 | 10/18 | 0.050 | ND | ND | ND | 0.270 | ND |
| 8. | 080 | (i)Analgesic (ii)Antipyretic | NIGERIA | A4-0536 | 9 | 2/14 | 1/18 | 0.250 | 0.033 | 0.194 | ND | 0.448 | 0.90 |
| 9. | 090 | (i)Analgesic (ii)Antipyretic | NIGERIA | 04-0261 | 3417T | 7/14 | 7/19 | 0.050 | ND | ND | 0.066 | 0.198 | 0.52 |
| 10. | 010 | (i)Analgesic (ii)Antipyretic | NIGERIA | 04-2307 | G0972 | 3/14 | 2/17 | 0.150 | 0.003 | ND | ND | 0.181 | 0.30 |
| 11. | 011 | (i)Analgesic (ii)Antipyretic | NIGERIA | 04-7108 | 314 | 08/12 | 07/16 | 0.250 | 0.003 | 5.298 | ND | 0.228 | 0.59 |
| 12. | 012 | (i)Analgesic (ii)Antipyretic | NIGERIA | 04-7312 | 983 | 7/13 | 6/18 | 0.250 | 0.011 | 1.298 | ND | 0.258 | 0.45 |
| 13. | 013 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | 04-7711 | 1000125 | 10/14 | 10/17 | 0.150 | 0.107 | ND | ND | 0.262 | 0.19 |
| 14. | 014 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | A4-7884 | B3006 | 2/13 | 1/16 | 0.250 | ND | ND | 0.005 | 0.111 | ND |
| 15. | 015 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | 04-2146 | T54814 | 8/14 | 7/19 | 0.150 | 0.084 | 2.056 | ND | 0.046 | 0.05 |
| 16. | 016 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | 04-1860 | 0300346 | 4/14 | 3/19 | 0.050 | 0.072 | ND | ND | 0.143 | 0.15 |
| 17. | 017 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | 04-1233 | 3222535 | 12/12 | 12/17 | ND | 0.020 | ND | ND | 0.131 | 0.81 |
| 18. | 018 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | B4-1238 | M301 | 12/13 | 11/16 | 0.050 | 0.024 | ND | ND | 0.181 | 0.48 |
| 19. | 019 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | 04-4386 | 212090 | 04/13 | 03/17 | 0.050 | 0.048 | ND | ND | 0.162 | 0.40 |
| 20. | 020 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | 04-0005 | 154V | 8/14 | 8/17 | 0.350 | 0.037 | ND | ND | 0.199 | 1.09 |
| 21. | 021 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | 04-1234 | 224083 | 8/14 | 8/18 | 0.150 | 0.115 | ND | ND | 0.140 | 0.54 |
| 22. | 022 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | A4-0940 | 05 | 01/14 | 01/18 | ND | 0.087 | 0.449 | ND | 0.098 | 0.52 |
| 23. | 023 | (i) Analgesic (ii) Antipyretic (iii) Anti Inflammatory | NIGERIA | A4-2896 | 60 | 5/14 | 4/18 | ND | 0.057 | 0.163 | ND | 0.191 | 0.30 |
| 24. | 024 | (i) Analgesic (ii) Antipyretic (iii) Anti -00Inflammatory | NIGERIA | A4-7034 | UPF303 | 1/13 | 1/16 | 0.050 | 0.060 | ND | ND | 0.145 | 0.70 |
| 25. | 025 | (i) Analgesic (ii) Antipyretic (iii) Anti Inflammatory | NIGERIA | A4-0486 | 23 | 7/14 | 6/18 | 0.150 | 0.021 | 0.479 | ND | 0.339 | 1.11 |
| 26. | 026 | (i) Analgesic (ii) Antipyretic (iii) Anti Inflammatory | NIGERIA | A4-3769 | 39 | 5/13 | 4/16 | ND | 0.094 | ND | ND | 0.174 | 0.91 |
| 27. | 027 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | A4-0507 | PCT-120 | 6/12 | 5/16 | 0.050 | 0.079 | ND | 0.003 | 0.179 | 0.76 |
| 28. | 028 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | A4-6443 | JI29 | 9/11 | 8/15 | 0.050 | 0.144 | 0.809 | ND | 0.161 | 0.75 |
| 29. | 029 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | A4-8114 | J4079 | 3/14 | 2/17 | ND | 0.058 | ND | 0.008 | 0.337 | 1.16 |
| 30 | 030 | (i)Strong Analgesic (ii)Strong Antipyretic | NIGERIA | 04-5278 | 40303 | 3/14 | 2/18 | 0.150 | 0.042 | 0.648 | 0.053 | 0.201 | 1.00 |
NAFDAC-National agency for food, drug administration and control; Man date- Manufacturing date; Exp. Date- Expiry date.