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Dynamics of LOH formation in the tsa1 clone N and rad27 clone C lineages. Trajectory of the de novo LOH events in SK1/BY tsa1 clone N (Left) and rad27 clone C (Right) from passages 1 to 25. The first column is the parental clone. Gray: SK1/BY heterozygous markers; red: homozygous BY markers; blue: SK1 homozygous markers. In rad27, passages 2 and 3 were mosaic and are shown in SI Appendix, Fig. S6; passage 8 is omitted because the cells could not be recovered after storage.
