Table 1.
Demographics, clinical characteristics, and laboratory and radiology findings at admission day
| Total (n = 39) | Non-respiratory failure (n = 16) | Respiratory failure (n = 23) | P value | |
| Demographics and clinical characteristics | ||||
| Age (years) | 61 (49 to 74) | 63 (49 to 75) | 59 (50 to 70) | 0.7 |
| Sex | 0.3 | |||
| Female | 10 (25) | 6 (38) | 4 (17) | |
| Male | 29 (75) | 10 (62) | 19 (83) | |
| Comorbidity | ||||
| Hypertension | 7 (18) | 4 (25) | 3 (13) | 0.3 |
| Diabetes | 4 (10) | 2 (13) | 2 (9) | 0.7 |
| Chronic cardiac disease | 9 (23) | 4 (25) | 5 (22) | 0.8 |
| Chronic lung disease | 9 (23) | 5 (31) | 4 (17) | 0.3 |
| Cancer | 2 (5) | 2 (13) | 0 | 0.06 |
| Chronic kidney disease | 4 (10) | 2 (13) | 2 (9) | 0.7 |
| Symptoms before admission | ||||
| Fever (temperature ≥ 37.3 °C) | 34 (87) | 15 (94) | 19 (83) | 0.5 |
| Cough | 32 (82) | 14 (88) | 18 (79) | 0.5 |
| Sputum | 12 (31) | 3 (19) | 9 (38) | 0.2 |
| Sore throat | 11 (28) | 5 (31) | 6 (26) | 0.3 |
| Myalgia | 21 (54) | 11 (69) | 10 (44) | 0.04 |
| Fatigue | 30 (77) | 11 (69) | 19 (83) | 0.03 |
| Diarrhea | 8 (21) | 3 (19) | 5 (22) | 0.3 |
| Nausea or vomiting | 15 (39) | 6 (38) | 9 (39) | 0.3 |
| Shortness of breath | 23 (59) | 7 (44) | 16 (70) | 0.1 |
| Symptoms and scores at admission | ||||
| Need for oxygen therapy | 30 (77) | 9 (56) | 21 (91) | 0.02 |
| PO2/FiO2 ratio | 39 (30 to 45) | 47 (45 to 58) | 32 (22 to 39) | <0.01 |
| qSOFA score | 1 (0 to 1) | 0 (0 to 1) | 1 (0 to 1) | 0.07 |
| SOFA score | 2 (1 to 3) | 1 (0.5 to 2) | 2 (2 to 3) | 0.03 |
| NEWS score | 4.0 (1.8 to 7.0) | 3 (1.3 to 5.8) | 6 (3.5 to 8) | 0.3 |
| Time from first symptom to hospital admission, days | 8 (6 to 11) | 8 (5 to 11) | 9 (7 to 12) | 0.6 |
| Laboratory findings | ||||
| White blood cell count, x109/L | 5.6 (4.8 to 7.7) | 4.9 (4.1 to 5.7) | 6.6 (5.3 to 9.7) | <0.01 |
| Platelet count, x109/L | 191 (155 to 231) | 180 (150 to 204) | 198 (166 to 233) | 0.2 |
| D-dimer, mg/L | 0.8 (0.6 to 2.0) | 0.6 (0.4 to 1.0) | 1.0 (0.8 to 2.5) | 0.04 |
| Ferritin, µg/L | 796 (363 to 1355) | 498 (267 to 773) | 1112 (691 to 1476) | 0.01 |
| CRP, mg/L | 67 (31 to 146) | 50 (25 to 76) | 114 (44 to 153) | 0.05 |
Data are median (25th to 75th percentile) or n (percent). P values were calculated using Mann−Whitney U test, χ2 test, or Fisher’s exact test, as appropriate. P < 0.05 highlighted bold and italic. Respiratory failure is defined as PO2/FiO2 ratio <40 kPa.