Table 3. Diagnostic accuracy of the visual analysis, lesion-to-blood blood uptake ratio on early-phase scan, and lesion-to-bone uptake ratio on convention scan.
| Diagnostic ability | Early-phase scan | Convention scan | |||
|---|---|---|---|---|---|
| Visual analysis | Lesion-to-blood pool uptake ratio | Visual analysis | Lesion-to-bone uptake ratio | ||
| Cut-off value | – | 0.76 | – | 2.50 | |
| Sensitivity (%), (95% CI) | 96.4 (81.7–100.0) | 92.9 (76.5–99.1) | 100.0 (87.7–100.0) | 92.9 (76.5–99.1) | |
| Specificity (%), (95% CI) | 88.2 (79.4–94.2) | 81.2 (71.2–88.8) | 70.6 (59.7–80.0) | 42.4 (31.7–53.6) | |
| PPV (%), (95% CI) | 73.0 (60.0–82.9) | 61.9 (50.8–71.9) | 52.8 (44.6–60.9) | 34.7 (30.1–39.5) | |
| NPV (%), (95% CI) | 98.7 (91.6–100.0) | 97.2 (90.0–99.2) | 100.0 (93.5–100.0) | 94.7 (82.2–98.6) | |
| Accuracy (%) | 90.3 | 83.2 | 77.9 | 54.9 | |
| AUC (95% CI) | 0.923 (0.858–0.965) | 0.917 (0.850–0.960) | 0.853 (0.774–0.913) | 0.756 (0.666–0.832) | |
PET/CT, positron emission tomography/computed tomography; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the receiver operating characteristic curve.