Table 1.
Variable | Ncoma | Nparb | Effect size | Heterogeneity | Gradec | NNTd | ||||
g | 95% CI | I 2 | 95% CI | |||||||
All studies |
|
|
|
|
|
|
|
|
||
|
Active treatment controls | 5 | 403 | −0.55 | −1.18 to 0.08 | 87.52 | 73 to 94 | ++ | 3.31 | |
|
Passive controls | 20 | 1604 | 0.52e | 0.33 to 0.71 | 68.69 | 50 to 80 | ++ | 3.5 | |
|
|
One outlier removedf | 19 | 1558 | 0.46e | 0.29 to 0.63 | 58.49 | 31 to 75 | +++ | 3.91 |
Studies aimed at depression |
|
|
|
|
|
|
|
|
||
|
Active treatment controls | 4 | 351 | −0.70 | −1.51 to 0.11 | 90.63 | 79 to 96 | + | 2.63 | |
|
Passive controls | 13 | 1162 | 0.60e | 0.35 to 0.85 | 73.27 | 54 to 85 | ++ | 3.05 | |
|
|
One outlier removedf | 12 | 1116 | 0.51e | 0.30 to 0.72 | 61.76 | 28 to 80 | ++ | 3.55 |
aNcom: number of comparisons.
bNpar: number of participants.
c+: very low quality; ++: low quality; +++: moderate quality.
dNNT: number needed to treat.
eP<.001.
fOutlier Sethi (2013) excluded.