Table 4.
Adjusted associations with SCD assessed continuously via self-perceived cognitive function and SCD assessed categorically via endorsement of memory complaints, and final prediction models (n = 490)
| Self-perceived cognitive function (standardised) | Memory complaints (binary) | |||||
|---|---|---|---|---|---|---|
| Adjusted modelsa | ||||||
| Multivariable linear regression model | Multivariable logistic regression model | |||||
| Explanatory variables | Coefficient | 95% CI | p-value | Odds ratiob | 95% CI | p-value |
| Age (1 year) | − 0.002 | −0.02 to 0.02 | 0.850 | 1.03 | 0.98 to 1.08 | 0.258 |
| Female (vs male) | 0.15 | −0.01 to 0.31 | 0.063 | 0.85 | 0.54 to 1.34 | 0.477 |
| Education (1 year) | 0.01 | −0.01 to 0.04 | 0.238 | 1.02 | 0.95 to 1.09 | 0.586 |
| Repetitive negative thinking (1 SD) | −0.24 | − 0.36 to − 0.12 | < 0.001 | 1.64 | 1.16 to 2.31 | 0.005 |
| Rumination (1 SD) | −0.11 | −0.20 to − 0.01 | 0.026 | – | – | – |
| Worry (1 SD) | −0.12 | − 0.26 to 0.02 | 0.103 | 0.94 | 0.64 to 1.37 | 0.734 |
| Purpose in life (1 SD) | 0.12 | 0.02 to 0.21 | 0.017 | 0.96 | 0.74 to 1.25 | 0.768 |
| Conscientiousness (1 SD) | 0.10 | 0.02 to 0.18 | 0.011 | 0.84 | 0.67 to 1.06 | 0.146 |
| Extraversion (1 SD) | 0.06 | −0.02 to 0.14 | 0.169 | – | – | – |
| Agreeableness (1 SD) | 0.03 | −0.05 to 0.11 | 0.482 | – | – | – |
| Neuroticism (1 SD) | −0.05 | −0.16 to 0.07 | 0.418 | 1.18 | 0.86 to 1.62 | 0.306 |
| Final prediction modelsc | ||||||
| Multivariable linear regression model | Multivariable logistic regression model | |||||
| Explanatory variables | Coefficient | 95% CI | p-value | Odds ratiob | 95% CI | p-value |
| Age (1 year) | 0.001 | −0.02 to 0.02 | 0.931 | 1.03 | 0.98 to 1.08 | 0.256 |
| Female (vs. male) | 0.16 | 0.003 to 0.32 | 0.046 | 0.83 | 0.54 to 1.30 | 0.418 |
| Education (1 year) | 0.01 | −0.01 to 0.04 | 0.252 | 1.02 | 0.96 to 1.09 | 0.502 |
| Repetitive negative thinking (1 SD) | −0.52 | − 0.59 to − 0.44 | < 0.001 | 1.81 | 1.46 to 2.26 | < 0.001 |
One participant had missing data on repetitive negative thinking and thus all models include 490 participants. Abbreviations: SCD, subjective cognitive decline; SD, standard deviation; CI, confidence interval
aThe adjusted models include all explanatory variables with p < 0.01 in the univariable regression models. Age, sex, and education were retained based on their well-established association with dementia
bIn the multivariable logistic regression model, for binary explanatory variables (sex), the estimate describes the odds of memory complaints in one group relative to the reference category (indicated in parentheses) when controlling for all other variables in the model. For continuous explanatory variables, the estimate reflects the expected increase in the odds of memory complaints for a one unit increase (indicated in parentheses) in the explanatory variable when controlling for all other variables in the model
cThe final prediction models retained all predictors with p < 0.01 in the adjusted models. Age, sex, and education were retained based on their well-known association with dementia