Fig. 3.

Effect of RNA input and parasitaemia on transcriptome correlations of P. falciparum in vitro samples. a, b Heatmaps depicting correlations between whole transcriptome amplified from varying RNA inputs (for both, low (0.1%) and high (1%) parasitaemia) and a 3D7 IDC reference transcriptome, or b each other. c, d Heatmaps depicting correlations between whole transcriptome amplified from varying parasitaemia samples and c 3D7 IDC reference transcriptome, or d to each other. A constant total RNA input of 250 ng was used across all parasitaemia in (c) and (d). All data have been obtained using spotted oligo microarray hybridization. PCC values are shown here with maximum correlation coefficients marked as numerals in (a and c). HPI = hours post invasion