. 2020 Oct 10;20:277. doi: 10.1186/s12903-020-01267-4

Table 1.

Average value of Candida sp. (CFU/ml) and API and GBI indices (%) during the study for all patients

	T0	T1	T2	T3	Differences between stages
Candida colonization [CFU/ml count]	Average ± SD (range) Median	2.6 × 10² ± 4.3 × 10² (0–1.3 × 10³) 0 × 10²	5.2 × 10² ± 9.4 × 10² (0–3.0 × 10³) 1 × 10²	4.7 × 10² ± 7.6 × 10² (0–3.0 × 10³) 2 × 10²	10.7 × 10² ± 23.1 × 10² (0–8.5 × 10³) 1 × 10²	p = 0.9092 (Skillings–Mack Statistic)
API value [%]	Average ± SD (range) Median	40.9 ± 22 (13–94.8) 42.3	43.4 ± 22.6 (13.6–88.2) 38.0	38.3 ± 17.4 (10–66.7) 35.3	39.8 ± 23 (4.5–100) 35.0	p = 0.7968 (Friedman rank sum test; chi-squared)
GBI value [%]	Average ± SD (range) Median	10.3 ± 9 (0–25) 8.3	9.4 ± 8.8 (0–31.2) 7.5	19.23 ± 24.8 (0–93.8) 11.8	10.6 ± 8.5 (0–29.5) 12.5	p = 0.4929 (Friedman rank sum test; chi-squared)

Differences between stages

Candida colonization [CFU/ml count]

Average ± SD (range)

Median

2.6 × 10² ± 4.3 × 10² (0–1.3 × 10³)

0 × 10²

5.2 × 10² ± 9.4 × 10² (0–3.0 × 10³)

1 × 10²

4.7 × 10² ± 7.6 × 10² (0–3.0 × 10³)

2 × 10²

10.7 × 10² ± 23.1 × 10² (0–8.5 × 10³)

1 × 10²

p = 0.9092 (Skillings–Mack Statistic)

API value [%]

Average ± SD (range)

Median

40.9 ± 22 (13–94.8)

42.3

43.4 ± 22.6 (13.6–88.2)

38.0

38.3 ± 17.4 (10–66.7)

35.3

39.8 ± 23 (4.5–100)

35.0

p = 0.7968 (Friedman rank sum test; chi-squared)

GBI value [%]

Average ± SD (range)

Median

10.3 ± 9 (0–25)

8.3

9.4 ± 8.8 (0–31.2)

7.5

19.23 ± 24.8 (0–93.8)

11.8

10.6 ± 8.5 (0–29.5)

12.5

p = 0.4929 (Friedman rank sum test; chi-squared)

Legend: API approximal plaque index, GBI gingival bleeding index, SD standard deviation, CFU colony-forming unit