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. 2020 Sep 29;6(3):e001297. doi: 10.1136/rmdopen-2020-001297

Table 2.

Categories, ultrasound findings and statistics

GCA risk category (n) Vascular US Final diagnosis Sensitivity (%) (95% CI) Specificity (%) (95% CI) PPV(%) (95% CI) NPV
(%) (95% CI)
Prevalence (%) (95% CI) Accuracy (%)
(95% CI)
LR+
(95% CI)
LR−
(95% CI)
GCA (n) Non-GCA (n)
High (66) Positive 50 2 50/53 (94)
(8499)
11/13 (85)
(5598)
50/52 (96)
(8799)
11/14 (79)
(5492)
53/66 (80)
(6989)
(50+11)/66 (92) (8397) 6.13
(1.71,21.98)
0.07
(0.02,0.21)
Negative/ND 3 (3/0) 11 (7/4)
Intermediate (137) Positive 36 3 36/36 (100)
(90 100)
98/101 (97)
(9299)
36/39 (92)
(8097)
98/98 (100)
(-)
36/137 (26)
(1934)
(36+98)/137 (98) (94 100) 33.67
(11.04,102.64)
0.00
Negative/ND 0 (0/0) 98 (68/30)
Low (151) Positive 0 3 0/0 (undefined)
(−)
148/151(98)
(94 100)
0/3 (0)
(−)
148/148 (100) (−) 0/151(0)
(0.00,2.41)
(0+148)/151 (98)
(−)
Negative/ND 0 (0/0) 148 (78/70)
Total (354) Positive 86 8 86/89 (97)
(9099)
257/265 (97)
(9499)
86/94 (91)
(8496)
257/260 (99) (97 100) 89/354 (25)
(2130)
(86+257)/354 (97)
(9598)
32.01
(16.16,63.40)
0.03
(0.01,0.11)
Negative/ND 3 (3/0) 257 (153/104)

GCA, giant cell arteritis; LR+, positive likelihood ratio; LR−, negative likelihood ratio; ND, not done; NPV, negative predictive value; PPV, positive predictive value; US, ultrasound.