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. 2020 Oct 10;40(1):1–12. doi: 10.1007/s10096-020-04057-6

Table 2.

Demographics, comorbidities, clinical presentation, and timing of respiratory samples for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) and outcome

N 1350
Sex (N 1076), male percentage (%) 43.8
Age (N 160)
  Mean, years (range) 47.4 (4–91)
  SD, years 19.3
Age (including case series, N 780)
  Weighted arithmetic mean, years 47.7
Hospital admission, days after symptom onset (N 81), mean (SD) 6.1 (7.6)
Charlson comorbidity index (N 107), median [IQR] 0 [0–2]
Presence of comorbidity (N 287), % 34.5
Symptoms at presentation
  Fever (N 320), % 66.3
  Cough (N 317), % 52.3
  Dyspnea (N 254), % 19.3
  Nausea/diarrhea (N 276), % 8.3
  Arthro-myalgia (N 281), % 12.8
Peripheral WBC (N 27)
  Mean, /mmc (range) 6281.5 (2900–13,400)
  SD, /mmc 2858.0
Lymphocytes (N 33)
  Mean, /mmc (range) 1143.4 (60–2948)
  SD, /mmc 636.4
Neutrophils (N 22)
  Mean, /mmc (range) 4740.4 (1595.9–9648.0)
  SD, /mmc 2858.0
CRP (N 32)
  Mean, mg/dL (range) 2.8 (0.1–10.0)
  SD, mg/dL 2.9
Pneumonia (N 316), % 82.0
ICU admission (N 232), % 2.6
Treatment (N 270), % 85.2
First positive respiratory samples
  Days from symptoms onset (N 120), mean (SD) 6.2 (4.7)
  Fever (N 308), % 68.8
  Symptoms (N 284), % 87.7
  Type of samples (N 494)
    Swabs, % 98.8
    Salivary tests, % 0.4
    Sputum, % 0.8
    Tracheal aspirate, % 0
First negative respiratory samples
  Days from symptoms onset (N 111), mean (SD) 19.1 (10.2)
  Fever (N 1033), % 0.1
  Symptoms (N 324), % 28.7
  Type of samples (N 458)
    Swabs, % 98.3
    Salivary tests, % 0.4
    Sputum, % 1.1
    Tracheal aspirate, % 0.2
New positive respiratory samples
  Days from symptoms onset (N 123), mean (SD) 34.5 (18.7)
  Fever (N 805), % 5.7
  Symptoms (N 1195), % 27.9
  Type of samples (N 821)
    Swabs, % 97.7
    Salivary tests, % 0.2
    Sputum, % 1.9
    Tracheal aspirate, % 0.1
  SARS-CoV-2 IgG positivity (N 544), % 92.5
New negative respiratory samples
  Days from symptoms onset (N 76), mean (SD) 41.2 (21.5)
  Fever (N 113), % 0
  Symptoms (N 113), % 4.4
  Type of samples (N 100)
    Swabs, % 95.1
    Salivary tests, % 0.7
    Sputum, % 4.3
    Tracheal aspirate, % 0
Outcome (N 802)
  Recovery, % 91.6
  Improvement, % 5.1
  Still hospitalized, % 1.1
  Death, % 2.1

Abbreviations: N number of patients, STD standard deviation, IQR interquartile range, WBC white blood cells, CRP C-reactive protein, ICU intensive care unit