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. 2021 Jan 29;538:192–203. doi: 10.1016/j.bbrc.2020.10.012

Table 2.

Summary of affinity and neutralization data for cross-neutralization antibodies discussed in this review.

IgG SARS-CoV-2
SARS-CoV
KD (nM) Authentic IC50 (μg/ml) Pseudovirus IC50 (μg/ml) KD (nM) Pseudovirus IC50 (μg/ml)
CR3022 [31] <0.1 >400 N.D. <0.1 50–100 (authentic virus)
COVA1-16 [18,32] 0.2 0.75 0.02 125 29
H014 [45] 0.096 38.1 0.4a 0.37 0.1a
EY6A [14] 8 0.07, 20b N.D. N.D. N.D.
S309 [33] <0.001 0.079 0.5a <0.001 0.12–0.18

N.D. denotes not determined.

a

Data converted from original data when reported in other units.

b

Two IC50 values from different neutralization experiments are from Ref. [14].