TABLE 3.

Hemodynamic variables during the cerebrovascular reactivity test

	LSM		HSM		p‐value
	BASE	POST	BASE	POST	Time	Meal	Time × meal
Rest
MCAvmean (cm/s/mm Hg)	64 ± 11	66 ± 11	64 ± 9	67 ± 11	.004	.40	.26
PETCO2 (mm Hg)	42 ± 4	43 ± 2	43 ± 3	43 ± 3	.33	.32	.32
Heart Rate (bpm)	59 ± 12	59 ± 12	56 ± 11	57 ± 12	.03	.32	.21
MAP (mm Hg)	88 ± 7	90 ± 7	86 ± 7	90 ± 7	.01	.26	.24
Hypercapnia
MCAvmean (cm/s/mm Hg)	96 ± 22*	98 ± 19*	94 ± 17*	100 ± 18*	.007	.28	.28
PETCO2 (mm Hg)	60 ± 6*	60 ± 4*	60 ± 4*	60 ± 4*	.17	.33	.33
Heart Rate (bpm)	66 ± 14*	68 ± 14*	65 ± 14*	67 ± 12*	.002	.48	.21
MAP (mm Hg)	93 ± 6*	94 ± 7*	90 ± 9*	94 ± 7*	.004	.52	.20
Recovery
MCAvmean (cm/s/mm Hg)	57 ± 11*	58 ± 12*	58 ± 10*	57 ± 9*	.45	.96	.83
PETCO2 (mm Hg)	40 ± 5*	40 ± 5*	40 ± 4*	41 ± 4*	.35	.34	.34
Heart Rate (bpm)	60 ± 13*	61 ± 12*	59 ± 11*	60 ± 12*	.80	.65	.37
MAP (mm Hg)	88 ± 11	92 ± 9	89 ± 10	91 ± 13	.005	.38	.76
Hypocapnia
MCAvmean (cm/s/mm Hg)	41 ± 9 *	42 ± 10 *	40 ± 7 *	42 ± 9 *	.02	.44	.32
PETCO2 (mm Hg)	29 ± 3 *	30 ± 4 *	28 ± 3 *	29 ± 3 *	.35	.33	.34
Heart Rate (bpm)	70 ± 16 *	71 ± 16 *	68 ± 13 *	71 ± 14 *	.01	.72	.97
MAP (mm Hg)	86 ± 7 *	89 ± 7 *	85 ± 8 *	87 ± 7 *	.003	.28	.76

Data presented as mean ± SD. Each variable was analyzed using a Two‐way RM ANOVA (meal × time). The p‐values indicate the results from the Two‐Way RM ANOVA (meal × time). The CVR test was separately analyzed using a RM One‐Way ANOVA for each time point of the test (rest, hypercapnia, recovery, hypocapnia).

Abbreviations: BASE, baseline; HSM, high Na⁺ meal; LSM, low Na⁺ meal; MAP, mean arterial pressure; MCA_Vmean, middle cerebral artery mean velocity; P_ETCO₂, end‐tidal carbon dioxide; POST, postprandial.

^* p < .05 versus rest.

^† p < .05 versus recovery.