Table 3. Up-regulated genes in 10 immune system pathways between groups A and B, groups A and C.
A were the samples for goats of 1-month-old (group A), B were the samples for goats of 12- month-old (group B ), C were the samples for goats of 24-month-old (group C).
| Pathway | A-vs-B | A-vs-C | ||
|---|---|---|---|---|
| up-regulated genes | FDR | up-regulated genes | FDR | |
| T cell receptor signaling pathway | no | 1.14E−17 | no | 3.09E−19 |
| Intestinal immune network for IgA production | BCR IgA | 7.90E−15 | BCR IgA | 3.09E−11 |
| Antigen processing and presentation | HSP70 | 7.42E−13 | no | 1.12E−08 |
| Hematopoietic cell lineage | IgM,IgD | 8.40E−13 | IgM,IgD | 2.36E−11 |
| Natural killer cell mediated cytotoxicity | IgG | 4.13E−07 | IgG | 8.75E−06 |
| Chemokine signaling pathway | no | 1.11E−05 | no | 8.03E−05 |
| Leukocyte transendothelial migration | RhoGAP | 7.35E−05 | no | 2.53E−02 |
| Fc gamma R-mediated phagocytosis | IgG | 3.47E−04 | IgG | 1.76E−03 |
| Fc epsilon RI signaling pathway | PKC ,IgE | 1.47E−02 | PKC ,IgE | 2.69E−03 |
| Platelet activation | p190 | 3.51E−02 | no | 2.96E−03 |