Table 1.
Characteristics | Group 1 (Patients with COVID-19 pneumonia) n = 55 | Group 2 (Patients without COVID-19 pneumonia) n = 59 | p-(value) | ||
---|---|---|---|---|---|
Demographics and baseline characteristics of COVID-19 patients | |||||
Age (y) (mean, extremes, SD) | 68.5 ± 16.7 [32–96] | 45.6 ± 16.2 [19–97] | <0,001 | ||
Sex (Number, %) | Male | 32 (58.2) | 16 (27.1) | 0,001 | |
Health care worker (Number, %) | 8 (14.5) | 34 (57.6) | <0,001 | ||
Current smoking (Number, %) | 8 (14.5) | 7 (11.9) | 0,672 | ||
Comorbidities (Number, %) | No | 15 (27.3) | 41 (69.5) | <0,001 | |
Cardio-vascular diseases | Hypertension | 26 (47.3) | 5 (8.5) | <0,001 | |
Heart failure | 9 (16.4) | 1 (1.7) | 0,007 | ||
Othersa | 9 (16.4) | 5 (8.5) | 0.200 | ||
COPDb or asthma | 9 (16.4) | 5 (8.5) | 0,200 | ||
Immunosuppressionc | 2 (3.6) | 2 (3.4) | 0,664 | ||
Diabetes mellitus | 14 (25.5) | 2 (3.4) | 0,001 | ||
Malignancy | 7 (12.7) | 1 (1.7) | 0,024 | ||
Charlson comorbidity index (mean, extremes, SD) | 3.2 ± 2.8 [0–10] | 0.7 ± 1.6 [0–9] | <0,001 | ||
Clinical outcomes | |||||
Hospitalization (Number, %) | 52 (94.5) | 9 (15.3) | <0.001 | ||
Duration of hospitalization (days) (mean, SD, extremes) | 10.7 ± 9.9 [1–44] | 3 ± 2.8 [1–10] | 0.026 | ||
Oxygen therapy (Number, %) | 44 (80) | 3 (5.1) | <0.001 | ||
Days from illness onset to oxygenation (days) (mean, SD, extremes) | 6,22 ± 4,26 [1–21] | 7.66 ± 5.85 [1–12] | 0.582 | ||
Patients admitted or transferred to ICU (Number, %) | 12 (21.8) | 0 | <0,001 | ||
Days from conventional hospitalization to ICU admission (mean, SD, extremes) | 3,90 ± 2,87 [1–11] | – | – | ||
IMV (Number, %) | 9 (16.4%) | 0 | 0.001 | ||
Duration of hospitalization in ICU (mean, extremes, SD) | 12,27 ± 10,03 [2–37] | – | – | ||
Outcome (Number, %) | Discharge | 35 (63.6) | 58 (98.3) | <0.001 | |
Death | 20 (36.4) | 1 (1.7) | <0.001 |
Bold values signifies p-value < 0.05.
Defined by: cardiac arrhythmia, coronary heart disease, stroke, peripheral arterial obstructive disease and thromboembolic disease.
COPD: chronic obstructive pulmonary disease.
Defined by: transplantation, cirrhosis, long-term steroids therapy, immunomodulators treatments.