Table 2.
Clinical features of 114 COVID-19 patients in Nord Franche-Comte Hospital, France, 2020.
| Functional Signs | Group P (patients with pneumonia) n = 55 | Group NP (patients without pneumonia) n = 59 | p-(value) | ||
|---|---|---|---|---|---|
| General symptoms | |||||
| Fever (Number, (%)) | Fever ≥ 38 (objective) | 51 (92.7) | 41 (69.5) | 0.002 | |
| Feeling of fever | 54 (98.2) | 52 (88.1) | 0.038 | ||
| No fever neither feeling of fever | 1 (1.8) | 7 (11.9) | 0.062 | ||
| Highest temperature (mean, extremes, SD) | 39.2 ± 0.7 [38–40] | 38.6 ± 0.5 [38–40] | <0.001 | ||
| Fatigue (Number, (%)) | 53 (96.4%) | 54 (91.5) | 0.249 | ||
| Pain symptoms | |||||
| Myalgia (Number, (%)) | 39 (70.9) | 39 (66.1) | 0.581 | ||
| Arthralgia (Number, (%)) | 39 (70.9) | 36 (61) | 0.266 | ||
| Headache (Number, (%)) | Total | 25 (45.5) | 51 (86.4) | <0.001 | |
| Diffuse | 17 (30.9) | 25 (42.4) | 0.205 | ||
| Faciala | 8 (14.5) | 25 (42.4) | 0.001 | ||
| Othersb | 0 | 1 (1.7) | 1 | ||
| Respiratory symptoms | |||||
| Cough (Number, (%)) | 43 (78.2) | 49 (83.1) | 0.510 | ||
| Sputum production (Number, (%)) | 13 (23.6) | 10 (16.9) | 0.374 | ||
| Sneezing (Number, (%)) | 15 (27.3) | 17 (28.8) | 0.855 | ||
| Chest pain (Number, (%)) | 18 (32.7) | 15 (25.4) | 0.390 | ||
| Hemoptysis (Number, (%)) | 5 (9.1) | 1 (1.7) | 0.105 | ||
| Dyspnea (Number, (%)) | 40 (72.7) | 13 (22) | <0.001 | ||
| Neurologic symptoms | |||||
| Dysgeusia (Number, (%)) | 18 (32.7) | 36 (61) | 0.003 | ||
| Anosmia (Number, (%)) | 17 (30.9) | 37 (62.7) | 0.001 | ||
| Otorhinolaryngological symptoms | |||||
| Tinnitus (Number, (%)) | 5 (9.1) | 4 (6.8) | 0.737 | ||
| Sore throat (Number, (%)) | 9 (16.4) | 23 (39) | 0,007 | ||
| Hearing loss (Number, (%)) | 3 (5.5) | 2 (3.4) | 0.671 | ||
| Rhinorrhea (Number, (%)) | 17 (30.9) | 30 (50.8) | 0.031 | ||
| Nasal obstruction (Number, (%)) | 3 (5.5) | 22 (37.3) | <0.001 | ||
| Epistaxis (Number, (%)) | 4 (7.3) | 3 (5.1) | 0.710 | ||
| Ocular symptoms | |||||
| Conjunctival hyperemia (Number, (%)) | 2 (3.6) | 3 (5.1) | 1 | ||
| Tearing (Number, (%)) | 3 (5.5) | 4 (6.8) | 1 | ||
| Dry eyes (Number, (%)) | 3 (5.5) | 1(1.7) | 0.351 | ||
| Blurred vision (Number, (%)) | 2 (3.6) | 2 (3.4) | 1 | ||
| Gastro-intestinal symptoms | |||||
| Nausea (Number, (%)) | 19 (34.5) | 18 (30.5) | 0.646 | ||
| Vomiting (Number, (%)) | 8 (14.5) | 4 (6.8) | 0.177 | ||
| Diarrhea (Number, (%)) | 27 (49.1) | 27 (45.8) | 0.722 | ||
| Abdominal pain (Number, (%)) | 11 (20) | 15 (25.4) | 0.490 | ||
| Physical examination | |||||
| Respiratory rate > 22 (Number, (%)) | 32 (58.2) | 3 (5.1) | <0.001 | ||
| Sat 02 at admission (%) (mean, extremes, SD) | 92 ± 4.9 [77–100] | 96 ± 3.1 [90–100] | 0.001 | ||
| Duration of symptoms | |||||
| Duration of all symptomsc (days) (mean, extremes, SD) | 17.2 ± 9.3 [5–51] | 11 ± 5.4 [3–22] | <0.001 | ||
| Duration of fever (days) (mean, extremes, SD) | 10.8 ± 8.7 [0–46] | 3.7 ± 3.9 [0–16] | <0.001 | ||
| Duration of cough (days) (mean, extremes, SD) | 14.6 ± 11 [0–51] | 7.4 ± 5.9 [0–23] | <0.001 | ||
| Duration of anosmia (days) (mean, extremes, SD) | 10 ± 7.5 [3–21] | 8.6 ± 6 [1–28] | 0.559 | ||
Bold values signifies p-value < 0.05.
a
Facial headache defined by: frontal and/or retro-orbital headache.
b
In group NP (patients without pneumonia); only one patient complained of temporal headache.
c
Defined by the time between symptoms onset and recovery (resolution of all symptoms).