Table 2.
Dataset | p-value for association with MS status at top CD58 variant | p-value for association with MS status at top FCRL3 variant |
---|---|---|
Europeans | 3.32 × 10−32 | 3.24 × 10−6 |
African-Americans before conditioning | 2.51 × 10−3 | 1.80 × 10−2 |
African-Americans after conditioning on top CD58 variant | 1.10 × 10−1 | 1.97 × 10−2 |
African-Americans after conditioning on top CD58 and FCRL3 variants | 1.24 × 10−1 | 5.83 × 10−2 |
European dataset is the MS Chip association signal15. African-American dataset is the 2007 subset of the new cohort. The CD58 variant is rs12025416, and the FCRL3 variant is rs6681271.