Table 2.
Characterization of Young’s modulus changes with increasing compressive force (indentation depth) for all tissue types
| Group/tissue type | Young’s modulus for two indentations (xc), Pa |
Curve shift based on xc values | Significance | |
|---|---|---|---|---|
| xc1µm | xc2µm | |||
| Group (I), healthy (A) | 56.0 | 61.1 | H | **p≤0.01 |
| Group (II), meningothelial meningioma (B) | 50.0 | 52.7 | — | NS (p>0.05) |
| Group III, fibrous meningioma (C) | 62.7 | 69.0 | H | *p≤0.05 |
| Group IV, hemangiopericytoma (D) | 90.5 | 95.0 | H | ***p≤0.001 |
| Group V, metastatic adenocarcinoma (E) | 256.7 | 242.2 | L | ***p≤0.001 |
| Group VI, glioblastoma (F) | 115.2 | 168.8 | H | **p≤0.01 |
| Group VII, margin adjacent to glioblastoma (G) | 41.1 | 43.5 | H | *p≤0.05 |
Notes: Statistically significant differences between distributions calculated at 1 µm and 2 µm indentation depths tested using Kolmogorov–Smirnov test. H — compression stiffening, L — compression softening.
Abbreviations: *p≤0.05; **p≤0.01; ***p≤0.001; ns, p>0.05.