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Bone Cancer Study Design
| Test System ID: Species: Breed: Sex | Rat: Sprague-Dawley: Male | ||||
|---|---|---|---|---|---|
| Treatment | N | Dose (mg/kg) | Dose Vol. (mL/kg) | Route | Day of Admin./Frequency |
| Vehicle (Ethanol: Tween 80: Normal Saline – 1:1:8) | 13 | NA | 5 | IP | Day 0/1x |
| CAV1001 | 8 | 1 | 5 | IP | Day 0/1x |
| CAV1001 | 8 | 5 | 5 | IP | Day 0/1x |
| CAV1001 | 13 | 10 | 5 | IP | Day 0/1x |
| morphine | 13 | 6 | 2 | SQ | Day 0/1x |
Abbreviations: IP, intraperitoneal; SQ, subcutaneous.
