Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 6;16:2285–2296. doi: 10.2147/NDT.S265601

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Liu and Dong.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

miR-652 downregulation reverses the protective effect of NR4A2 shRNA on PC12 cells after OGD treatment. PC12 cells were co-transfected with NR4A2 + miR-652 or shNR4A2 + miR-652 inhibitor. (A) miR-652 expression in PC12 cells after co-transfection measured by RT-qPCR; (B) PC12 cell proliferation determined by CCK-8 assays; (C) apoptosis level of PC12 cells by flow cytometry; (D) cell cycle distribution of PC12 cells detected by flow cytometry; (E) the protein expression of Cyto C and Bcl-2 in PC12 cells evaluated by Western blot. All values were expressed as means ± SD from three independent experiments. One-way (panel (A and C)) or two-way ANOVA (panel (B, D and E)) followed by Tukey’s post hoc test was applied for comparison. *p < 0.05, **p < 0.01 vs PC12 cells transfected with NR4A2 + NC or shNR4A2 + InC.