Table 1.
n | DRIFT | n | Standard | |||
Mean (SD) or n (%) | Mean (SD) or n (%) | |||||
Total number of participants | 28 | 24 | ||||
Centre | ||||||
Bristol, UK | 28 | 23 (82%) | 24 | 19 (79%) | ||
Katowice, Poland | 3 (11%) | 4 (17%) | ||||
Glasgow, UK | 1 (4%) | 1 (4%) | ||||
Bergen, Norway | 1 (4%) | 0 (0%) | ||||
Sociodemographics at birth | ||||||
Age at randomisation (days) | 28 | 18.68 (5.00) | 24 | 19.17 (4.53) | ||
Sex: male* | 28 | 22 (79%) | 24 | 15 (63%) | ||
Clinical characteristics at birth | ||||||
Birth weight (g)* | 28 | 1101.89 (335.54) | 24 | 1322.46 (534.68) | ||
Gestation (weeks) | 28 | 27.64 (2.56) | 24 | 28.50 (3.05) | ||
Grade of IVH: 4 | 28 | 14 (50%) | 24 | 11 (46%) | ||
Maternal age at birth | 14 | 28.50 (6.99) | 12 | 28.17 (6.32) | ||
Median IMD 2010, postcode at birth† (IQR) | 18 | 26.7 (8.2–36.5) | 18 | 27.6 (11.2–45.8) | ||
Measures at 2 years | ||||||
Experienced second IVH* | 28 | 8 (29%) | 24 | 3 (13%) | ||
VP shunt | 28 | 11 (39%) | 24 | 8 (33%) | ||
Ventricular access device* | 28 | 13 (46%) | 24 | 19 (79%) | ||
Measures at 10 years | ||||||
Age at 10-year assessment (years) | 28 | 10.56 (1.07) | 24 | 10.76 (1.06) | ||
Weight (kg) | 28 | 35.41 (10.05) | 23 | 34.73 (10.51) | ||
Height (cm) | 28 | 139.09 (12.22) | 23 | 142.26 (11.34) | ||
Head circumference (cm) | 28 | 52.88 (2.53) | 23 | 52.00 (3.43) | ||
Maternal education* | ||||||
Left school at 16 | 28 | 10 (36%) | 23 | 11 (48%) | ||
Further education | 6 (21%) | 5 (22%) | ||||
University degree | 12 (43%) | 7 (30%) |
*Difference of 10%/0.5 SD or higher between the groups.
†English Index of Multiple Deprivation (IMD) 2010 scores, UK Data Service Census Support (http://geoconvert.mimas.ac.uk/). Higher scores indicate higher levels of deprivation. IMD based on the children’s home postcode at birth for those residing in England only.
DRIFT, drainage, irrigation and fibrinolytic therapy; IVH, intraventricular haemorrhage; VP, ventriculoperitoneal.