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. 2020 Jan 13;105(5):489–495. doi: 10.1136/archdischild-2019-318474

Table 3.

Logistic regression analysis with different outcome variables: primary outcome, effective sedation and hypotension

Primary outcome
(n=89)
Effective sedation
(n=83)
Hypotension
(n=82)
OR 95% CI P value OR 95% CI P value OR 95% CI P value
Gestational age (weeks) 0.94 0.77 to 1.15 0.54 1.00 0.80 to 1.23 0.98 1.09 0.94 to 1.26 0.26
Birth weight <10th percentile (yes/no) 0.85 0.22 to 3.34 0.82 1.07 0.27 to 4.27 0.93 1.55 0.52 to 4.25 0.47
Male gender (yes/no) 1.72 0.46 to 6.40 0.42 2.67 0.76 to 9.36 0.13 0.94 0.36 to 2.45 0.90
Postnatal age (in hours) 1.00 0.99 to 1.00 0.69 1.00 0.99 to 1.00 0.65 1.00 0.99 to 1.00 0.45
Starting dose of propofol (mg/kg) 4.50 0.92 to 22.11 0.06 57.04 7.58 to 429.49 <0.001 1.09 0.35 to 3.39 0.88
Cumulative dose of propofol (mg/kg) 0.74 0.48 to 1.14 0.18

Corrected by Firth’s method to reduce bias because of relatively small sample size.