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. 2020 Oct 10;9(10):89. doi: 10.1038/s41389-020-00273-z

Fig. 5. TAp63α mediates SFN-suppressed colorectal CSC-like properties.

Fig. 5

HCT116 and SW480 spheres were used to measure the role of TAp63α/Lgr5/β-catenin axis in SFN-suppressed colorectal CSCs. A Western blot analysis for the protein levels of TAp63α, Lgr5, and β-catenin. B Sphere-forming assay was used to determine the size and number of spheres. C Western blot analysis for the protein levels of TAp63α, Lgr5 and β-catenin. D Western blot analysis for the protein levels of CD133, CD44, Nanog, and Oct-4. E Densitometric analyses of western blotting. Data are expressed as mean ± SD, n = 3. *p < 0.05, **p < 0.01, compared with control group. #p < 0.05, ##p < 0.01, compared with SFN group.