Fig.1.

Representative of the microscopic slide sections of the colon samples in rats: (A) Normal colon sample magnification (x 40), showed the normal structure of mucosa with an intact epithelial surface, submucosa, and muscular layer. (B) Normal colon sample, magnification (x 100), showed the normal structure of layers. (C) Acetic acid-induced colitis with no treatment, magnification (x 40), showed an inflammatory reaction, presence of ulcer, inflammation, edema, and diffuse infiltration of leukocytes in the submucosal layer. (D) Acetic acid-induced colitis with no treatment, magnification (x 200), showed inflammation in the submucosal layer with ulceration and edema. (E) Acetic acid-induced colitis+oral administration of sulfasalazine, magnification (x 40), revealed inflammatory reaction in the serosa layer. (F) Acetic acid-induced colitis+oral administration of sulfasalazine sample, magnification (x 100) revealed inflammatory reaction with the dominance of lymphocyte and fewer neutrophils with tissue necrosis. (G), (H) Acetic acid-induced colitis+oral administration of aloe vera gel, magnification (x 40), and (x 100), revealed the improvement of inflammation and the normal tissue.