Table 2.
Causes of Iron Overload
| Anatomical Location or Mechanism | Causes | |
|---|---|---|
| Hereditary or acquired metabolic disorder | Hemochromatosis (hereditary or secondary) | |
| Porphyria cutanea tarda | ||
| Metabolic syndrome | ||
| Chronic hepatopathies | Hepatitis | Viral |
| Auto-immune | ||
| Toxic | Alcoholic | |
| Steatosis | Alcoholic | |
| Non-alcoholic | ||
| Hematological mechanism | Myelodysplastic syndrome | |
| Hemophagocytic lymphohistiocytosis | ||
| Excessive iron intake | Iterative transfusions | Thalassemia |
| Homozygous sickle cell disease | ||
| Sideroblastic anemia | ||
| Iron administration | Dialysis | |
| High level athletes | ||
| Other | Ferroportin mutation | |
| Hereditary aceruloplasminemia | ||