. 2020 Oct 7;12:9765–9774. doi: 10.2147/CMAR.S273328

Table 2.

Univariate and Multivariate Logistic Analyses of the Risk Factors Associated with Lymph Nodes Metastasis

Variables	Univariate Analysis			Multivariate Analysis
Variables	OR	95% CI	P value	aOR	95% CI	P value
Gender
Male	1
Female	0.797	0.585–1.085	0.149
Age (year)	0.997	0.981–1.014	0.745
Smoking
Current or ex	1
Never	0.813	0.588–1.125	0.211
PLT (×10^9/L)	1.006	1.004–1.009	0.000^a	1.004	1.001–1.007	0.010^a
Tumor location
LUL	1
LLL	1.075	0.669–1.728	0.764
RUL	0.577	0.375–0.888	0.012^a
RML	0.669	0.330–1.357	0.265
RLL	1.101	0.707–1.716	0.669
Surgery
Limited resection	1
Lobectomy	1.058	0.556–2.016	0.863
Pneumonectomy	15.769	1.686–147.509	0.016^a
Tumor size (cm)	1.921	1.678–2.200	0.000^a	1.699	1.471–1.963	0.000^a
Predominant subtype
L	1			1
A	12.379	4.477–34.227	0.000^a	10.430	3.693–29.457	0.000^a
P	10.440	3.559–30.622	0.000^a	6.779	2.228–20.633	0.001^a
MP	102.000	26.144–397.946	0.000^a	68.016	16.734–276.455	0.000^a
S	43.385	14.727–127.805	0.000^a	19.235	6.262–59.082	0.000^a
IMA	13.655	4.064–45.880	0.000^a	5.952	1.587–22.332	0.008^a
STAS
Absent	1
Present	0.989	0.594–1.648	0.967
VPI
Absent	1			1
Present	2.162	1.481–3.156	0.000^a	1.635	1.053–22.332	0.029^a
MVI
Absent	1			1
Present	5.210	3.223–8.422	0.000^a	3.074	1.773–5.330	0.000^a

Notes: P value, OR, and 95% CI were calculated using the Chi-square test and Fisher’s exact test. aOR, adjusted odds ratio. ^a Statistically significant.

Abbreviation: CI, confidence interval.