Table 3.
nab-PTX followed by FEC (n = 50) | ||||
Adverse events | nab-PTX | FEC | ||
All Grade
n (%) |
Grade 3
n (%) |
All Grade
n (%) |
Grade 3
n (%) |
|
Neutropenia | 3 (6.0) | 2 (4.0) | 6 (12.0) | 3 (6.0) |
Anemia | 0 | 0 | 2 (4.0) | 2 (4.0) |
Hepatopathy | 5 (10.0) | 1 (2.0) | 0 | 0 |
Stomatitis | 2 (4.0) | 0 | 12 (24.0) | 1 (2.0) |
Fatigue | 4 (8.0) | 0 | 21 (42.0) | 1 (2.0) |
Constipation | 3 (6.0) | 0 | 8 (16.0) | 0 |
Nausea | 1 (2.0) | 0 | 13 (26.0) | 1 (2.0) |
Arthralgia | 26 (52.0) | 0 | 1 (2.0) | 0 |
Peripheral neuropathy | 48 (96.0) | 0 | 24 (48.0) | 0 |
Rash | 11 (22.0) | 3 (6.0) | 2 (4.0) | 0 |
Anaphylactic shock | 0 | 0 | 0 | 0 |
Keratitis | 0 | 0 | 1 (2.0) | 0 |
Fever | 4 (8.0) | 0 | 1 (2.0) | 0 |
Hand foot syndrome | 1 (2.0) | 0 | 2 (4.0) | 0 |
Diarrhea | 0 | 0 | 3 (6.0) | 0 |
Edema | 1 (2.0) | 0 | 2 (4.0) | 0 |
Blurred vision | 1 (2.0) | 0 | 1 (2.0) | 0 |
Myalgia | 1 (2.0) | 0 | 0 | 0 |
FEC: 5-fluorouracil, epirubicin, and cyclophosphamide, nab-PTX: nanoparticle albumin-bound paclitaxel.