Skip to main content
. 2020 Oct 7;13:9991–10000. doi: 10.2147/OTT.S268214

Figure 2.

Figure 2

miR-135b-5p suppresses expression of AR protein in HCC cells. (A) The effect of miR-99b, miR-101, miR-135b-5p, miR-373, and miR-375 on expression of AR protein in SK-hep1 and HA22T cells. Analysis by Western blot assay revealed that miR-135b-5p could significantly suppress AR protein expression in SK-hep1 and HA22T cells. (B) The effect of miR-135b-3p on expression of AR protein in HepG2, SNK, and Huh7 cells. Analysis by Western blot assay revealed miR-135b-5p could significantly suppress AR protein expression in HepG2 and Huh7. Western blot assays were performed as described in Materials and Methods. (C) miR-135b-5p suppresses AR expression unless AR is overexpressed in SK-hep1 and HA22T cells. (D) miR-135b-5p suppresses HCC proliferation unless AR is overexpressed in SK-hep1 and HA22T cells. **p < 0.01, ##p < 0.01.