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. 2019 Nov 6;24:209–217. doi: 10.1016/j.jot.2019.10.005

Figure 1.

Figure 1

A-D) CMS-induced bone formation in the C6 vertebra ​at early stage. (A) The three-dimensional reconstructive images of the C6 vertebra. (B) The microstructure analysis of cancellous bone at the C6 vertebra, CMS significantly increased the BV/TV, Tb.N, and Tb.Th, whereas decreased the Tb.Sp at 4 weeks. (C, D) Representative HE staining and Col I staining in the C6 vertebra. All data were shown as mean ​± ​SD (n ​= ​8). “*” indicated P ​< ​0.05 compared with the sham group. BV/TV = bone volume fraction; Tb.N = trabecular number; Tb.Th = trabecular thickness; Tb.Sp = trabecular separation; HE staining = haematoxylin–eosin staining.