Table 3.

Health states probability, cost, and utility

	Base probabilitya	Cost ($)b	Utilityb
Acute GU (first cycle)
Acute GI Grade 2 toxicity	0.1133	730.0746–48	0.786749
Acute GI Grade ≥3 toxicity	0.0019	11,147.7946–48,50	0.50351,52
Acute GU Grade 2 toxicity	0.2258	452.7947	0.798349
Acute GU Grade ≥3 toxicity	0.0158	8,109.5047,53	0.4354,55
Chronic SE (cycles 2+)
Chronic GI Grade 2 toxicity	0.0117	730.0746–48	0.786749
Chronic GI Grade ≥3 toxicity	0.0051	11,147.7946–48,50	0.50351,52
Chronic GU Grade 2 toxicity	0.0178	452.7947	0.798349
Chronic GU Grade ≥3 toxicity	0.0040	8,109.5047,53	0.4354,55
Recurrence (Biochemical)	0.0229c	14,011.7556,57	0.4958
Non-cancer death	0.0397d	0	0.00
Cancer death	0.0036e	0	0.00

GI, gastrointestinal;GU, genitourinary.

^aBase probabilities were obtained from averages in Table 2.

^bFull cost and utility breakdown is available in Appendix B.

^cA probability of 0.18 was used for recurrence to remain in the recurrence health state.⁵⁹

^dBased on a 66 year old male with a 17.2 year life expectancy.¹⁸

^eA probability of 0.03 was used for recurrence to transition to the cancer death health state.⁶⁰