Figure 3.

Increased dendrite length in iNeurons derived from KO iPSC clones. A, Representative images of eGFP-expressing iNeurons from the four different clones at DIV45. Scale bars: Inset, 200 µm. B–E, Histograms represent average length per cell of total (B), primary (C), secondary (D), and tertiary dendrites (E) of the four clones. F–I, Graphs represent average number of dendrites per cell of total (F), primary (G), secondary (H), and tertiary (I) dendrites of the four clones. In box-and-whisker plots, the middle, boxes, and whiskers represent the median, interquartile range, and min to max, respectively. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.