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. 2020 Oct 12;5(7):625–632. doi: 10.1016/j.oret.2020.09.024

Table 4.

Complications Observed after Intravitreal Injection

Complication Type No. of Total Injections (%)
Any complication 841 (1.9)
Any minor complication 612 (1.4)
 Irritation 312
 Subconjunctival hemorrhage 284
 Air bubble 79
 Medication in eye 40
Any serious complication 157 (0.4)
 Corneal abrasion 46
 Iritis 31
 Vitreous hemorrhage 24
 Increased intraocular pressure 22
 Posterior vitreous detachment 12
 Conjunctivitis 11
 Hyphema 6
 Vitreous cell 5
 Conjunctival abrasion 5
 Medication in anterior chamber 4
 Corneal edema 3
 Retinal tear 2
 Rhegmatogenous retinal detachment 2
 Other 19
Any unrelated complication 124 (0.3)
 No acute pathologic features 80
 Progressing disease 44

Complications totaled 1031 in 841 encounters, because a patient could demonstrate multiple complications.

Includes one of each of the following: central artery occlusion, complication diagnosed by outside provider, conjunctival inclusion cyst, debris in vitreous cavity, decreased vision, disc edema, episcleritis, exudative retinal detachment, headache, limbal flush, lower eyelid abnormality, macular hole, periorbital ecchymosis, preseptal cellulitis, retained cilia, scleritis, subhyaloid or intraretinal hemorrhage, vitreomacular traction, and vitreous opacity.