Table 1.
Summary of newborn screening programs initiated in India.
| State | District | Target Population | Sample | Technology for Screening | No. Screened | No(%)AS | No(%)SCD | Follow Up | Reference |
|---|---|---|---|---|---|---|---|---|---|
| South Gujarat Phase 1 |
Valsad | All Tribal babies | Heel prick-Dried blood spot | HPLC-Variant NBS machine | 5467 | 687 (12.5%) |
46 (0.8%) |
5–6 years | Italia et al., 2015 [18] |
| South Gujarat Phase 2 |
Valsad, Bharuch | All Tribal babies | Heel prick-Dried blood spot | HPLC-Variant NBS machine | 2944 | 649 (22.0%) |
76 (2.6%) |
2 years | Unpublished |
| Maharashtra | Nagpur | Largely non-tribal, babies of AS mothers | Cord blood, heel prick | HPLC-Variant Hb Testing System | 2134 | 978 (45.8%) |
113 (5.3%) |
4-5 years | Upadhye et al., 2016 [19] |
| Madhya Pradesh | Jabalpur | Tribal, babies of AS mothers | Cord blood, heel prick | HPLC-Variant Hb Testing System | 461 | 36 (7.8%) |
6 (1.3%) |
1 year | Unpublished |
| Chhattisgarh | Raipur | Tribal and non-tribal babies | Heel prick-Dried blood spot | HPLC-Variant NBS machine | 1158 | 61 (5.3%) |
6 (0.5%) |
No follow up reported | Panigrahi et al., 2012 [20] |
| Odisha | Kalahandi | Tribal and non-tribal babies | Heel prick-Dried blood spot | HPLC-Variant Hb Testing System | 1668 | 293 (17.6%) |
34 (2.0%) |
No follow up reported | Mohanty et al., 2010 [21] |
| Odisha | Kalahandi | Tribal babies | Cord blood | HPLC-Variant Hb Testing System | 761 | 112 (14.7%) |
13 (1.7%) |
No follow up reported | Dixit et al., 2015 [22] |
| Tripura | Agartala | Tribal & non tribal babies | Cord blood | HPLC-Variant Hb Testing System | 2400 | 15 (0.6%) |
0 (0.0%) |
Not done | Upadhye et al., 2018 [23] |
| Maharashtra | Chandrapur | Tribal and non-tribal babies | Cord blood, heel prick | HPLC-Variant Hb Testing System | 1010 | 85 (8.4%) |
4 (0.4%) |
Not done | Unpublished |