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. 2020 Oct 7;13:3469–3484. doi: 10.2147/IDR.S265699

Table 4.

Activity of immature juvenile Schistosoma mansoni in PSO- and PZQ-treated groups after different incubation periods (IPs)

IP (hours) Groups n Worm activity p-value
Score 0,
n (%)
Score 1,
n (%)
Score 2,
n (%)
Score 3,
n (%)
24 Untreated 100 0 0 0 100 (100) <0.001
P1: <0.001
P2: <0.001
P3: <0.001
P4: <0.001
P5: 0.043
PZQ 100 2 (2) 2 (2) 0 96 (96)
PSO (100) 100 94 (94) 4 (4) 2 (2) 0
PSO (80) 100 78 (78) 22 (22) 2 (2) 0
PSO (60) 100 27 (30) 65 (65) 6 (6) 2 (2)
PSO (40) 100 0 4 (4) 91 (91) 5 (5)
PSO (20) 100 0 0 0 100 (100)
48 Untreated 100 0 0 0 100 (100) <0.001
P1: <0.001
P2: <0.001
P3: <0.001
P4: <0.001
P5: < 0.001
PZQ 100 4 (4) 4 (4) 0 92 (92)
PSO (100) 100 100 (100) 0 0 0
PSO (80) 100 100 (100) 0 0 0
PSO (60) 100 71 (71) 19 (19) 3 (3) 7 (7)
PSO (40) 100 52 (52) 30 (30) 14 (14) 0
PSO (20) 100 48 (48) 25 (25) 22 (22) 5 (5)
72 Untreated 100 0 0 0 100 (100) <0.001
P1: <0.001
P2: <0.001
P3: <0.001
P4: <0.001
P5: <0.001
PZQ 100 10 (10) 0 0 90 (90)
PSO (100) 100 100 (100) 0 0 0
PSO (80) 100 100 (100) 0 0 0
PSO (60) 100 100 (100) 0 0 0
PSO (40) 100 90 (90) 7 (7) 3 (3) 0
PSO (20) 100 75 (75) 19 (19) 1 (1) 5 (5)

Abbreviations: P1, comparison between Pzq and PSO (100); P2, comparison between Pzq and PSO (80); P3, comparison between Pzq and PSO (60); P4, comparison between Pzq and PSO (40); P5, comparison between Pzq and PSO (20).