Table 1.
TTR variant | Mutation | Oligomeric state in solution |
---|---|---|
M-TTR | F87M/L110M | Monomer |
NSTTR | N99R/S100R | Tetramer |
T119M | T119M | Tetramer |
WT | None | Tetramer |
A108R/L110R | A108R/L110R | Tetramer + dimer + monomer |
M13R/L17R | M13R/L17R | Dimer + monomer |
S112I | S112I | Dimer |
L55P | L55P | Tetramer |
L55P/T119M | L55P/T119M | Tetramer |