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. 2020 Oct 2;24:100822. doi: 10.1016/j.bbrep.2020.100822

Table 1.

The effect of placebo and rosuvastatin treatment on the concentration of the main variables in this study.

Variable Absolute concentration (mean ± SD)
Difference PB – BL (% mean change) Difference RS – BL (% mean change)
Baseline (BL) Placebo (PB) Rosuvastatin (RS)
Total cholesterol, mmol/L 6.17 ± 0.47 6.16 ± 0.44 3.81 ± 0.33 −0.01 ± 0.06a (−0.16) −2.36 ± 0.14e (−38.25)
LDL-cholesterol, mmol/L 4.57 ± 0.32 4.56 ± 0.30 2.18 ± 0.19 0.01 ± 0.06a (0.22) −2.39 ± 0.13e (−52.29)
HDL-cholesterol, mmol/L 1.175 ± 0.15 1.186 ± 0.14 1.273 ± 0.16 0.011 ± 0.02a (0.93) 0.098 ± 0.02b (8.34)
Apolipoprotein B-100, nmol/L 322.34 ± 46.91 321.90 ± 47.52 175.02 ± 19.15 −0.44 ± 4.54a (−0.13) −147.31 ± 31.24c (−45.70)
Apolipoprotein A-1, nmol/L 37.11 ± 3.44 37.17 ± 3.50 39.17 ± 3.47 0.05 ± 0.28a (0.13) 2.06 ± 0.14e (5.55)
Triglycerides, mmol/L 0.93 ± 0.078 0.94 ± 0.063 0.74 ± 0.065 0.01 ± 0.03a (1.08) −0.19 ± 0.02d (−20.43)
Phospholipids, mmol/L 2.45 ± 0.10 2.46 ± 0.12 1.78 ± 0.05 0.01 ± 0.03a (0.41) −0.67 ± 0.06d (−27.35)
Total fatty acids, mmol/L 13.11 ± 0.54 13.17 ± 0.50 9.16 ± 0.28 0.06 ± 0.22a (−0.46) −3.95 ± 0.29e (−30.13)
Total free fatty acids, μmol/L 683.55 ± 29.58 682.06 ± 26.17 537.22 ± 18.36 −1.49 ± 9.54a (−2.18) −146.33 ± 18.12d (−21.41)

ap > 0.05; bp < 0.001; cp < 0.0001; dp < 0.00001; ep < 0.000001.