Table 4. Select Rat PK Parameters for 10.
| Rat
IV PK, 5 mpk |
Rat
PO PK, 5 mpk |
|||||
|---|---|---|---|---|---|---|
| t1/2 (h) | Vss (L/kg) | Clp (L/h/kg) | AUC (μM·h) | Cmax (μM) | AUC (μM·h) | F (%) |
| 9.4 | 0.29 | 0.13 | 71.2 | 5.54 | 11.7 | 17 |
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