Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| Table
6A: Rat IV PK, 5 mpk |
Rat
PO PK, 5 mpk |
|||||
|---|---|---|---|---|---|---|
| t1/2 (h) | Vss (L/kg) | Clp (L/h/kg) | AUC (μM·h) | Cmax (μM) | AUC (μM·h) | F(%) |
| 3.9 | 0.18 | 0.08 | 94.9 | 1.97 | 12.5 | 13 |
| Table
6B: CD-1 Mouse IV PK, 5 mpk |
CD-1
Mouse PO PK, 5 mpk |
|||||
|---|---|---|---|---|---|---|
| t1/2 (h) | Vss (L/kg) | Clp (L/h/kg) | AUC (μM·h) | Cmax (μM) | AUC (μM·h) | F(%) |
| 2.4 | 0.43 | 0.22 | 34.5 | 1.46 | 3.81 | 11 |
