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. 2020 Sep 19;23(10):101581. doi: 10.1016/j.isci.2020.101581

Figure 7.

Figure 7

NIM811 Induces Tumor Necrosis and Inhibits Lymph Node Metastasis in TNBC Xenografts

(A) Quantification of the necrotic area of primary tumor based on histologic examination of H&E-stained sections. Percent of total necrotic area determined by a board-certified pathologist. Bars, mean ± SEM. ∗∗∗p < 0.005. One-way ANOVA with Dunnett's test was used to determine significance.

(B) Lymph node metastases were detected by histologic examination of H&E-stained section of lymph nodes harvested from mice treated for 12 weeks with either NIM811 or vehicle control. ∗∗p < 0.01, ∗∗∗p < 0.005. One-way ANOVA with Dunnett's test was used to determine significance.