Table 9.
Groups, sex and dose (mg/kg) | Fasting body weight (g) Mean ± SD | Brain | Heart | Liver | Kidney | Thymus | Spleen | Lungs | Testis | Epididymis |
---|---|---|---|---|---|---|---|---|---|---|
G1 M 0 | 191.68 | 0.92 | 0.35 | 4.02 | 0.91 | 0.13 | 0.48 | 0.96 | 1.45 | 0.30 |
19.15 | 0.10 | 0.03 | 0.34 | 0.13 | 0.06 | 0.10 | 0.67 | 0.13 | 0.05 | |
G2 M 50 | 189.75 | 0.91 | 0.36 | 4.13 | 0.88 | 0.09 | 0.38 | 0.69 | 1.44 | 0.26 |
8.99 | 0.06 | 0.00 | 0.56 | 0.10 | 0.04 | 0.14 | 0.07 | 0.10 | 0.05 | |
G3 M 100 | 163.82 | 1.25 | 0.46 | 5.62 | 1.12 | 0.10 | 0.80 | 0.99 | 1.94 | 0.28 |
38.21 | 0.15 | 0.14 | 2.73 | 0.44 | 0.04 | 0.87 | 0.37 | 0.59 | 0.11 | |
G4 M 150 | 174.95 | 0.98 | 0.35 | 3.72 | 0.91 | 0.10 | 0.21 | 0.76 | 1.54 | 0.34 |
11.67 | 0.11 | 0.04 | 0.39 | 0.08 | 0.02 | 0.07 | 0.15 | 0.16 | 0.07 |
G5-toxicokinetic group
Values are in Mean ± SD; G1 vs G2, G3 & G4 (*p < 0.05)