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. 2020 Feb 14;11(10):1881–1885. doi: 10.1021/acsmedchemlett.9b00555

Figure 1.

Figure 1

Stereodiagram of the X-ray cocrystal structure of compound 3 bound in the active site of COX-2 (PDB code 6V3R). An omit map is contoured at 3σ in black mesh. The key residues are illustrated with a stick representation of the final model (carbon in yellow, oxygen in red, nitrogen in blue), and compound 3 is colored in green.