Skip to main content
. 2020 Jul 15;11(10):2017–2023. doi: 10.1021/acsmedchemlett.0c00176

Table 3. Pharmacokinetic Profiles of 2a, 2c, 2g, and BBR.

Compound R1 Cmaxa (μg/mL) Exc.b (%)
2a H 0.89 5.9
2c I 5.95 0.02
2g Cyclopropyl 1.36 0.35
BBR   4.42 0
a

Maximum concentration (Cmax).

b

Excretion rate in urine (%, 0–4 h) after oral administration of 3 mg/kg to rats.